Photobiomodulation for
Wellness
Transcranial photobiomodulation (tPBM) has a wide range of wellness benefits for healthy individuals, including improved cognitive function, reduced inflammation, and enhanced mood.
In this page, we will explore the research behind these benefits and discuss the potential of tPBM for improving overall wellness.
Improved Cognitive Function:
One of the primary benefits of tPBM is improved cognitive function. Several studies have found that tPBM can enhance learning and memory in healthy individuals.The mechanism behind these cognitive benefits is thought to be related to increased blood flow and oxygenation in the brain. tPBM stimulates the mitochondria in brain cells, which produces more ATP, the energy currency of the cell. This increased energy production leads to improved cellular function and enhanced cognitive performance.
Reduced Inflammation:
tPBM has also been shown to enhance mood in healthy individuals. The mechanism behind these mood-enhancing effects is thought to be related to increased production of serotonin and dopamine, two neurotransmitters that are involved in mood regulation. tPBM stimulates the production of these neurotransmitters in the brain, leading to enhanced mood and reduced symptoms of anxiety and depression.
Improve Sleep:
tPBM may also enhance sleep quality and duration in individuals with sleep disorders or those who just want to work on improving sleep. One of the proposed mechanisms for PBM's effect on circadian rhythm is its ability to stimulate the production of melatonin, a hormone that plays a crucial role in regulating the sleep-wake cycle. Melatonin is produced in the pineal gland in response to darkness and is suppressed by light exposure.
Another proposed mechanism is PBM's ability to activate specific receptors in the eye that are involved in regulating circadian rhythm. In particular, the melanopsin-containing ganglion cells in the retina are sensitive to light and play a critical role in regulating the circadian rhythm. By stimulating these receptors, PBM may help to reset the circadian rhythm and improve sleep quality.
Check below more studies on PBM for general wellness:
2. Cassano P, Petrie SR, Hamblin MR, Henderson TA, Iosifescu DV. Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis. Neurophotonics. 2016 Jul;3(3):031404. doi: 10.1117/1.NPh.3.3.031404. Epub 2016 Mar 4. PMID: 26989758; PMCID: PMC4777909. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777909/
3. Naeser MA, Zafonte R, Krengel MH, Martin PI, Frazier J, Hamblin MR, Knight JA, Meehan WP 3rd, Baker EH. Significant improvements in cognitive performance post-transcranial, red/near-infrared light-emitting diode treatments in chronic, mild traumatic brain injury: open-protocol study. J Neurotrauma. 2014 Jun 1;31(11):1008-17. doi: 10.1089/neu.2013.3244. Epub 2014 May 8. PMID: 24568233; PMCID: PMC4043367. https://pubmed.ncbi.nlm.nih.gov/24568233/
4. Schiffer F, Johnston AL, Ravichandran C, Polcari A, Teicher MH, Webb RH, Hamblin MR. Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety. Behav Brain Funct. 2009 Dec 8;5:46. doi: 10.1186/1744-9081-5-46. PMID: 19995444; PMCID: PMC2796659. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796659/
5. Jahan, Ali et al. “Transcranial Near-Infrared Photobiomodulation Could Modulate Brain Electrophysiological Features and Attentional Performance in Healthy Young Adults.” Lasers in medical science 34.6 (2019): 1193–1200. Web. https://link.springer.com/article/10.1007/s10103-018-02710-3
6. Qu, Xiujuan et al. “Repeated Transcranial Photobiomodulation Improves Working Memory of Healthy Older Adults: Behavioral Outcomes of Poststimulation Including a Three-Week Follow-Up.” Neurophotonics (Print) 9.3 (2022): 035005–035005. Web. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514540/
7. Valverde A, Hamilton C, Moro C, Billeres M, Magistretti P, Mitrofanis J. Lights at night: does photobiomodulation improve sleep? Neural Regen Res. 2023 Mar;18(3):474-477. doi: 10.4103/1673-5374.350191. PMID: 36018149; PMCID: PMC9727457. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727457/
8. Fernandes MP, Vidal CL, de Oliveira TT, Botelho AL, Valente MLDC, Dos Reis AC. Effects of photobiomodulation on auriculotherapy points for sleep disorders, anxiety, and temporomandibular dysfunctions. Cranio. 2020 Dec 7:1-6. doi: 10.1080/08869634.2020.1853896. Epub ahead of print. PMID: 33287687. https://pubmed.ncbi.nlm.nih.gov/33287687/
9. Semyachkina-Glushkovskaya O, Fedosov I, Penzel T, Li D, Yu T, Telnova V, Kaybeleva E, Saranceva E, Terskov A, Khorovodov A, Blokhina I, Kurths J, Zhu D. Brain Waste Removal System and Sleep: Photobiomodulation as an Innovative Strategy for Night Therapy of Brain Diseases. Int J Mol Sci. 2023 Feb 6;24(4):3221. doi: 10.3390/ijms24043221. PMID: 36834631; PMCID: PMC9965491. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965491/
Further Research
Clinical research is ongoing and several studies have been published on light therapy for various conditions.
Take a look below to explore each research page.
Neuronic is not providing any medical advice. Neuronic devices are not medical devices under any jurisdiction and are not intended to diagnose, treat, cure or prevent any disease.
Neuronic is not providing any medical advice. We advise you to consult a medical professional and conduct your own independent research.
Neuronic devices are not medical devices under any jurisdiction and are not intended to diagnose, treat, cure or prevent any disease.
Continue Reading
Continue reading below to learn more about photobiomodulation on a cellular level and understand the difference between wavelength and frequency.
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